Trap Columns
Trapping is a chromatography technique that allows for the concentration or purification of a sample. A trap cartridge is a packed column bed loaded with a material to create desirable conditions for separating the target compound from the rest of the sample matrix. This is accomplished by selecting a packing material that has a strong affinity for the target compound, causing the analyte to be retained in the trap while the rest of the sample matrix flows through, or by selecting a material which has no affinity for the target compound but that binds other unwanted matrix components such as salts, detergents and contaminants.
To learn more about LC or LC/MS off-line and on-line trapping, please take a look at our publication: LC Trapping – A Practical Guide to Techniques and Products.